The Claypool Laboratory
The Claypool Laboratory
  • Welcome to the Mitochondrial Phospholipid Research Center


    where science is FUN and RIGOROUS

    Johns Hopkins university

    The  Johns Hopkins School of Medicine is the original research-driven  hospital. We have an established and rich tradition of training the next  generation of doctors and scientists that continues to this day.



    Mission Statement

    The research mission of the Department of Physiology is to explore how the complex cellular phenotypes that underlie the integrated functions of the tissues and organ systems comprising higher living organisms, emerge from the genomic code. Our research program extends from computational methods to developmental genetics and post-genomic strategies—from bacteria and yeast, to zebrafish, mouse, and man.

    What can we do you for?

    We Welcome You

    Welcome  to The Mitochondrial Phospholipid Research Center  a.k.a. The CLAYPOOL  Lab in the Department of Physiology at the Johns Hopkins  University  School of Medicine. 

    We are an eclectic group of scientists who recognize   that phospholipids are really, really, really important. Although  second in the  cell with respect to its lipid synthesizing capacity, the  mitochondrion is number  one in our hearts. Using biochemical and cell  biologic approaches, we seek to comprehensively  understand any and all  aspects of mitochondrial phospholipid metabolism as it  relates to human  health and disease. 

    Frequent Ask Questions

      What is your lab philosophy?

    To  identify important biological questions and then  develop comprehensive and  clever strategies to establish likely  answers.   In other words, don’t suck.

    How did your lab become a research center?
    As a  group, we made the decision that we were in fact not just a lab, but a center.       
    Dr. Claypool, how do you explain your dearth of awards?
     Once  you meet me, you’ll understand.


    Postdoctoral Fellows:  We currently are recruiting one postdoctoral  fellow. A suitable  candidate will have an established expertise in  biochemistry, cell  biology, or biophysics; familiarity with the fields of  mitochondrial  biology or lipid metabolism; excellent communication skills in  English;  and a strong publication record. Postdoctoral fellows interested in   seeking independent funding are particularly encouraged to apply.  Interested  candidates should send a CV, brief summary of research  experience and  interests, and the names of three references to Prof.  Steven Claypool.   

    Graduate Students: Motivated rotons are always welcome. We seek to  integrate 1-2 new graduate students into our group.

    What's Happening!?!?




    • Seun defended his thesis, graduated and is now at the Emory University School of Medicine
    • Seun’s paper that determined that Aac2p function regulates complex IV biogenesis is accepted at Molecular Biology of the Cell
    • Hawa Sidy is our current SARE Student

    Contact Us

    Better yet, see us in person!

    Claypool Lab

    1915 E Madison St, Baltimore, Maryland 21205, United States

    Where science is FUN and RIGOROUS

    Principal Investigator

    Steven Claypool, Ph.D.

    Associate Professor of Physiology
     Department of Physiology
    725 N. Wolfe Street
       Hunterian Building, Room 205
    Baltimore, MD 21205
    Phone 410.614.1786